This is one of the most commonly asked questions by patients when it comes to skin injectables. If you happen to not know any of the treatments on the title, you can refer to one of our posts here: 

Why did we compare these treatments? 

These 3 treatments are similar in a few ways, and to the layperson, it is also these similarities that confuse us to think that they are the same:

  1. They are all injectable treatments, usually delivered in the form of multiple injections on the skin of the face either manually or with an injector. 
  2. They improve ageing skin which typically is plagued with dryness, fine lines, and laxity. 
  3. They do not change the shape of our faces. 
  4. Profhilo and Skinboosters both contain hyaluronic acid (HA) like dermal fillers, but due to structural differences, they do not add to volume in the face. 

So, which treatment is the best? 

Well, there is no right answer to this question. Profhilo is not better than skin boosters and vice versa, and the same applies to Rejuran. The right question to ask rather is: 

“Which is the best treatment for me?”

All 3 treatments have their own special qualities and have been proven to be effective in their respective domains, giving significant results if done properly. More importantly, it is imperative and essential that the treatment that is chosen is best suited to target the patient’s unique skin needs and concerns. These concerns could be skin laxity, dryness, skin texture, pore size, scars, uneven skin tone or even all of them. 

Below, we will first look at some basic differences between these 3 products: 

InjectableHA contentPain ScoreFrequencyEffects
Profhilo64mg/syringe2ml
per syringe
2/102 sessions,
1 month apart
Hydration
Plumps skin
Improves skin quality
Reduces skin laxity
Modest lifting effect
Skinboosters15-20mg/syringe1ml/syringe4/103-4 sessions,
1 month apart
Hydration
Skin brightening
Rejuran Healer0mg2ml/syringe6/103-4 sessions,
1 month apart
Improve skin quality
Minimal hydrating effect

So, who will benefit from which treatment?

Skinboosters

What are skinboosters and who will benefit most from Skinboosters?

Skinboosters are colloquially known as injectable moisturizers. It is a treatment that is based on multiple micro-injections of free hyaluronic acid into the skin to increase the hydration level in the skin. HA is a water-binding molecule that is able to hold up to 10,000 times its own weight in water. Common brands include Restylane Vital Lite and Teosyal Redensity I. 

Patients who primarily want to improve skin dryness as well as want some glow and radiance to their complexion will benefit most from skinboosters.

A course of skin booster treatment involves 3 sessions one month apart to achieve long-lasting radiance. Downtime is typically 3-5 days due to the many injection points and depth of injection, typically as small injection marks, although bruising is also a possibility. Skin boosters can be administered via manual hand injections by your doctor or using an injector, or a mixture of both. 

Rejuran

What is Rejuran and who will benefit most from Rejuran?

Rejuran is an injectable based on polynucleotide derived from Salmon DNA from Korea. Its main benefits are creating skin healing and collagen synthesis. 

Patients who have acne scars, open pores, sensitive skin, uneven skin tone as well as redness stand to benefit most from Rejuran injections. 

Rejuran injections also require a minimum of 3 sessions, one month apart. Due to the superficial nature of the injections – it is placed in the superficial layer (basement membrane) of the skin, patients get “mosquitoes bites-like bumps” immediately after treatment that typically take 24-48 hours to subside. Injection marks may remain for up to 3 days, but bruising is exceedingly rare. 

Profhilo

What is Profhilo and who will benefit most from Profhilo? 

Profhilo is an injectable based on both high molecular weight and low molecular weight HA which had been treated with just thermal reaction to form hybrid cooperative complexes. It works by multilevel dynamic remodelling, and hence in addition to skin hydration, it also stimulates collagen production and improves skin laxity. 

Patients with ageing skin that is affected by both dryness, laxity and loss of elasticity with early sagging will benefit most from Profhilo treatment. 

Profhilo requires 2 sessions one month apart due to the presence of cooperative hybrid complexes which renders it more resistant to hyaluronidase breakdown. 

Profhilo also has the advantage of requiring only 5 injection points on each side of the face using the Bio-Aesthetic Points (BAP) technique which means the treatment only causes minimal downtime in the form of swelling over the injection points that usually subside within the day. In all 3 treatments, Profhilo has the least downtime due to this. 

Below is a summary table comparing the 3 products 


ProfhiloSkinboosterRejuran
IngredientsH-HA & L-HAFree HAsPolynucleotides
BenefitsHydration
Multilevel bio-remodelling
Collagen+Elastin production
HydrationRadianceSkin barrier rejuvenationSkin repairCollagen production
TargetAgeing skin with laxity and early saggingDry skinSensitive skin, open pores, acne scars, uneven skin tone, redness
Age group30-50yo for anti-ageingSagging thinned skin20yo above with dry, dehydrated dull skin20yo above with problematic, acne or sensitive skin
Administration BAP techniques – 5 injections per sideMultiple manual microinjections with hand or injectorMultiple manual microinjections with hand or injector
Treatment Regime2 sessions, 4 weeks apart3-4 sessions 1 month apart3-4 sessions 1 month apart
Duration of efficacy6-9 months6 months6 months
DowntimeMinimal downtime – mild swelling on injection pointsInjection marks 3-5 days with risk of bruisingInsect bite like swelling for 24-48 hours, injection marks 2-3 days
Treatment areasFace, neck, décolletage, arms, handsFace, neck, décolletage, handsFace, neck, hands
Combination with other treatmentsYesYesYes
Pain Score+++++++++
Price$$$$$$$

So, which treatment is right for you? 

This really depends on your skin concern and what you are looking to achieve with treatment. There is no “one size fits all” solution in aesthetic practice and it is always advisable to speak in detail with your doctor about what you want to achieve. 

As social media becomes an increasingly larger part of our social lives, be it group photos taken at events, or selfies that we post onto our own profiles, we are also increasingly pressured to look the way we have portrayed our digital avatars. 

PHOTO EDITING, SELFIES AND BEAUTY APPS

Photo editing used to be available to only the highest echelons of society, mainly in the form of airbrushed pictures and videos seen in the media.

The advent of beauty and social apps such as Meitu, Instagram and Snapchat in recent years have vastly changed this. Now, every social class in society who has access to a smartphone has the ability to use the various facial filters and editing options to edit their photos and make adjustments to facial features to control the image they portray online. This has redefined the perception of beauty and has allowed us to enhance and beautify our facial and body features in a few clicks and swipe. It has allowed us to take control of our public face in the virtual realm. As a result, wide ranges of “selfies” have since populated the vast social media, ranging from minor edits to completely unnatural looking photos such as the infamous “snake man” from China.

FAKE PIC?

However, despite the now-common phenomenon of photo editing, the advent of these tools has also fuelled new insecurities, such as “what if people noticed?”, “oh, that must have been an edited picture”, “he does not look like that in real life” etc. Also, there is often a fear of not putting your best foot forward – for example, not getting a job or not getting the second date for not looking like the photo in your CV or profile. These have as a result fuelled both insecurities as well as aspirations to look more like our digital images or avatars. 

In the last decade or so, the once-taboo topic of having aesthetic procedures done is now increasingly becoming more mainstream and better accepted socially. Indeed, the acceptance of cosmetic and facial plastic surgery has increased and it is an increasingly common sight to see people discussing what they had done at dinner events, or even overhear discussions about trips to foreign countries for aesthetic and plastic surgical procedures. It is also more common for people to turn up in aesthetic and plastic surgery clinics requesting to look like their app-edited selfies. 

JUST VAIN OR “SNAPCHAT DYSMORPHIA” AT PLAY?

The phenomenon, as it becomes more common, is also attracting more discussions and opinions. Singaporean media TODAY published an opinion recently discussing how doctors in aesthetic and plastic surgery clinics are getting an increasing number of patients requesting to look more like their app-edited selfies, and the concern of how much mental health issues such as body dysmorphia disorder and low self-esteem is at play when it comes to wanting to improve one’s looks.

Rightly so, aesthetic treatments will not treat a fundamental psychological problem and patients who truly have body dysmorphia disorder will not attain satisfaction from aesthetic treatments and in fact may go down a slippery slope of repeatedly seeking enhancements without ever getting satisfaction. 

CAN I LOOK LIKE MY SELFIE?

The desire to enhance one’s look is not new. Selfie-editing apps, however, have now brought the idea of editing how one looks to the masses. After seeing enhanced versions of themselves, people want to be able to control how some of their facial features look. Of course, most people will only want minor improvements, such as a smoother complexion, sharper-looking features, removing their eye bags or dark circles, a more lifted face. Realistic requests and expectations are usually achievable although people also have to be prepared to accept some deviation from their desired results occasionally. 

WHAT CAN BE DONE

With aesthetic and plastic surgery procedures receiving more acceptance, the million dollar question is now whether achieving one’s desired look is possible. 

There are a host of treatments to address particular concerns, and when used in combination, they can generally achieve the ‘wants’, albeit minor deviation from the desired results occasionally. 

Patients who want a clearer complexion may undergo treatments to improve skin texture and tone such as light based therapies the likes of Intense Pulsed Light (IPL) treatments and lasers, chemical peels, rejuvenation injections such as Rejuran and skin boosters as well as botox and fillers to lighten the appearance of wrinkles. People with acne scars may consider lasers, peels and injection based treatments such as Rejuran S to lighten and ameliorate the scars over time. 


Read More: Look Refreshed with Restylane Skinbooster

To alter facial features however, a combination of skin tightening treatments, contouring treatments, fillers, thread lifts, botox, or even the more invasive plastic surgery may be used to enhance features such as a higher nose bridge, more defined jaw, slimmer face, higher cheekbones, or even fuller lips; and to reduce the appearance of undesirable features such as a double chin, sagging jowls, deep smile or laugh lines, frown lines, crow’s feet etc. By enhancing the aesthetically pleasing features and reducing the appearance of undesirable features, aesthetic doctors can often rejuvenate and freshen up one’s appearance.

One other common concern is tired eyes. Although most people put this down to having insufficient sleep, the factors causing this is much more complex than that. Tired looking eyes is usually due to a combination of pigmentation in the under eye area, lax skin around the eye, venous congestion as well as herniation of the fat pad under the eye that becomes worse with age. To achieve the ‘eye bag’ function that face editing apps achieve, a combination of treatments including light based therapies such as lasers, fillers and polynucleotide injections, chemical peels, topical skin care as well as addressing age related volume loss in the cheek area, are typically employed to rejuvenate the eyes. 

Read more:
Rejuran i – Everything You Need to Know

As evident from above, there are many options and ways of dealing with particular aesthetic concerns. However, the perception of beauty and facial features varies greatly, not only between cultures, but also between individuals. This is also the reason why customization and tailoring a personalized treatment plan to each individual is so important. 

THE PRICE OF BEAUTY

All these however come at a price. In an ideal world, everyone will want every treatment that can keep them looking like they were in their 20s. However, as with any procedures, there will be a cost to it. The cost of cosmetic procedures have always been perceived to be high and only accessible to the highest echelons of society. 

In Singapore, the growing aesthetic market has attracted the attention of multiple stakeholders. Over the past decade, the number of aesthetic providers have been steadily increasing. With the increased numbers of providers, costs have been on a downward trend over the past decade. Average prices for procedures have fallen over the years and consumers are having an increasing number of choices in terms of providers as well as treatment options. 

Despite this however, misled by the outdated perception that procedures in medical clinics are costly, some people have unwittingly attended unscrupulous beauty parlours that provide aesthetic procedures illegally, sometimes with dire consequences such as infections, blindness, skin necrosis, disfiguring scars etc. 

There are also people who travel abroad to countries like Thailand or South Korea for cosmetic surgical procedures. While people often get satisfactory results, cosmetic surgeons and practitioners in Singapore are often left to manage complications or revisions from botched surgery overseas. 

WHERE DO I START?

Everyone has a different motivation in wanting to improve their appearance. The first and foremost important question to answer is if that motivation is warranted and valid. Beyond that, other things such as invasive vs. non-invasive procedures, expectations, desired results also make important considerations. Although reading up from validated websites is also a good way to start, readers will have to be cautious of the source, quality and truth of the information they obtain, as every individual responds differently to treatments and there is a lot of misleading half-truths on the world wide web. Having friends who have done it first-hand to speak to will also be helpful and the final step will be to speak to one or even two trusted doctor to understand the procedures, the possible outcomes, risks and treatment plan to definitively address the aesthetic concern before embarking onto the journey of looking like your selfie. 

See also: rejuran, rejuran healer

Author: Dr Kwan Yuan Dong

Dr Kwan is a medical aesthetic doctor in S Aesthetics Clinic, Singapore. He is passionate in educating the public about medical aesthetic procedures, skin care and anti-ageing treatment.


*DisclaimerInformation provided in this article is for reference and educational purposes only. It does not replace actual medical advice and consultation with your doctor.

Restylane Refresh Products can help to continuously improve your skin’s condition, expanding versatility, and diminishing scarcely discernible differences and blemishes. An invigorated look can be accomplished with Restylane Skinbooster medications and Restylane Skincare line. – Skinbooster

Restylane Skinboosters – Feel the distinction in your skin

Do you wish for skin with a brilliance and smoothness that you will see, feel and love? Restylane® Skinboosters™ will make you feel extraordinary about your skin once more.

After a couple of medications, as prompted by your specialist you’ll see that your skin will move toward becoming smoother, progressively brilliant, and increasingly flexible. The skin of your face, hands, neck and décolletage can be improved. The outcomes can improve things significantly to the manner in which you feel about your skin.

Restylane Skinboosters have been utilized by aesthetics doctors for more than 12 years and over 3.5 million such procedures have been performed in that time.

  • Infusions are ordinarily directed through the span of 2-3 treatment sessions, 2– a month separated, to reestablish your skin’s versatility and smoothness step by step.
  • Customary upkeep sessions (roughly at regular intervals) happen as arranged with your specialist guaranteeing enduring outcomes.

Clinical investigations demonstrate the enduring effect of a Restylane Skinboosters treatment with progress in skin flexibility of the face and hands for as long as a year after the underlying treatment.

Treatment zones

Restylane Skinboosters is a flexible and successful answer for skin worries in the face, neck, décolletage and hands.

The Pros – Skinbooster

Restylane SkinBoosters (水光针) treatment renews your skin by presenting a delicate, characteristic hyaluronic corrosive filler into your skin by means of microinjections. The advantages of experiencing the treatment are:

  • Incremental hydration of the skin
  • Diminish appearance of wrinkles
  • Produce radiant, shining skin in a natural manner
  • Giving enduring hydration
  • Improve generally speaking skin surface by plumping up lacking regions and wrinkles to give a smoother appearance

Will there be any adverse reactions?

Some regular reactions associated with Restylane Skinboosters treatment are gentle redness, swelling or wounding on the locales where the treatment is managed. We offer post-treatment care in the facility to help you sooth your skin and lessen the redness. You may anticipate that the gentle redness and swelling should resolve by itself in a day or two.

Any arrangement required before the treatment?

Keep away from sustenance and enhancements that can thin the blood, for example, liquor, NSAIDS, nutrient E, garlic, ginseng for 2 days before going for treatment.

For best outcomes, you ought to likewise maintain a strategic abstinence from strenuous activities for a day or two after the treatment.

What else would be a good idea for me to observe?

For iridescent, shining skin with the best outcomes, ensure that it is performed by a medicinal specialist who utilizes Restylane fillers. Restylane Skinboosters alludes to a treatment that utilizes Restylane Vital and Restylane Vital Light. These fillers contain the correct mixes to give your skin the dependable hydration that you are searching for.

Skinbooster is good for:

Individuals who have dull skin with barely recognizable differences, who need to accomplish brilliant, firmer and supple skin.